Rimonabant reduces keratinocyte viability by induction of apoptosis and exerts topical anti-inflammatory activity in mice

BACKGROUND AND PURPOSE: There is growing evidence that the cannabinoid CB(1) receptor antagonist, rimonabant (SR141716) exerts potential anti-proliferative and anti-inflammatory actions. Here, we have assessed the effects of rimonabant in vitro in murine immortalized keratinocytes and in vivo by ass...

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Dettagli Bibliografici
Autori principali: Malfitano, Anna Maria, Sosa, Silvio, Laezza, Chiara, De Bortoli, Marco, Tubaro, Aurelia, Bifulco, Maurizio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2011
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012408/
https://ncbi.nlm.nih.gov/pubmed/20880029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01047.x
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