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Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase.

Focal adhesion kinase (pp125FAK or FAK) and paxillin colocalize with integrins in structures called focal adhesions. pp125FAK plays an important role in the transmission of integrin-induced cytoplasmic signals. Paxillin has also been implicated in cell signaling by virtue of its association with the...

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Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Hildebrand, J D, Schaller, M D, Parsons, J T
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7579684/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.6.6.637
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