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Rap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formation.

We developed new image analysis tools to analyse quantitatively the extracellular-matrix-dependent cell spreading process imaged by live-cell epifluorescence microscopy. Using these tools, we investigated cell spreading induced by activation of the small GTPase, Rap1. After replating and initial adh...

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Autori principali: Sarah H Ross, Emma Spanjaard, Anneke Post, Marjolein J Vliem, Hendy Kristyanto, Johannes L Bos, Johan de Rooij
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2012-01-01
Serie:PLoS ONE
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23209645/pdf/?tool=EBI
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