Mitochondrial Biogenesis and Peroxisome Proliferator–Activated Receptor-γ Coactivator-1α (PGC-1α) Deacetylation by Physical Activity: Intact Adipocytokine Signaling Is Required

OBJECTIVE: Transcriptional peroxisome proliferator–activated receptor-γ coactivator-1α (PGC-1α) plays a key role in mitochondrial biogenesis and energy metabolism and is suggested to be involved in the exercise-induced increase in mitochondrial content. PGC-1α activity is regulated by posttranslatio...

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Hlavní autoři: Li, Ling, Pan, Ruping, Li, Rong, Niemann, Bernd, Aurich, Anne-Cathleen, Chen, Ying, Rohrbach, Susanne
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2011
Témata:
Obesity Studies
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012167/
https://ncbi.nlm.nih.gov/pubmed/20929977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0331
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