Sphingosine 1-phosphate (S1P) promotes mitochondrial biogenesis in Hep G2 cells by activating Peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α)

Sphingosine 1-phosphate (S1P), a potent bioactive phospholipid, has been reported to regulate a broad spectrum of biological processes. However, little is known regarding S1P’s effects on mitochondrial function. In this study, we investigated the S1P’s effects on the Peroxisome proliferator-activate...

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Detalhes bibliográficos
Main Authors: Shen, Zhixin, Liu, Chong, Liu, Pingping, Zhao, Jiamin, Xu, Wanpeng
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4041936/
https://ncbi.nlm.nih.gov/pubmed/24293320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-013-0480-5
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