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The non-redundant role of N-WASP in podosome-mediated matrix degradation in macrophages

Wiskott-Aldrich Syndrome Protein (WASP) is a hematopoietic cell-specific regulator of Arp2/3-dependent actin polymerization. Despite the presence of the highly homologous N-WASP (neural-WASP), macrophages from WAS patients are devoid of podosomes, adhesion structures in cells of the monocytic lineag...

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Autors principals: Nusblat, Leora M., Dovas, Athanassios, Cox, Dianne
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012153/
https://ncbi.nlm.nih.gov/pubmed/20732727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2010.07.012
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