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The non-redundant role of N-WASP in podosome-mediated matrix degradation in macrophages
Wiskott-Aldrich Syndrome Protein (WASP) is a hematopoietic cell-specific regulator of Arp2/3-dependent actin polymerization. Despite the presence of the highly homologous N-WASP (neural-WASP), macrophages from WAS patients are devoid of podosomes, adhesion structures in cells of the monocytic lineag...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3012153/ https://ncbi.nlm.nih.gov/pubmed/20732727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2010.07.012 |
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