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Expression of IMP1 Enhances Production of Murine Leukemia Virus Vector by Facilitating Viral Genomic RNA Packaging

Murine leukemia virus (MLV)-based retroviral vector is widely used for gene transfer. Efficient packaging of the genomic RNA is critical for production of high-titer virus. Here, we report that expression of the insulin-like growth factor II mRNA binding protein 1 (IMP1) enhanced the production of i...

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Detalhes bibliográficos
Main Authors: Mai, Yun, Gao, Guangxia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012120/
https://ncbi.nlm.nih.gov/pubmed/21209918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015881
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