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Understanding the Sequence-Dependence of DNA Groove Dimensions: Implications for DNA Interactions

BACKGROUND: The B-DNA major and minor groove dimensions are crucial for DNA-protein interactions. It has long been thought that the groove dimensions depend on the DNA sequence, however this relationship has remained elusive. Here, our aim is to elucidate how the DNA sequence intrinsically shapes th...

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Detalhes bibliográficos
Main Authors: Oguey, Christophe, Foloppe, Nicolas, Hartmann, Brigitte
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012109/
https://ncbi.nlm.nih.gov/pubmed/21209967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015931
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