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Thymine-methyl/π interaction implicated in the sequence-dependent deformability of DNA

The crystal structures of deoxy-oligonucleotides were retrieved from the Nucleic Acid Database and analyzed with the use of our program CHPI. The structure of 5′-ApTpApT-3′ has been shown to be stabilized by the 5-methyl group in the thymidine moiety that favorably interacts with the adenine π-ring...

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Detalhes bibliográficos
Main Authors: Umezawa, Yoji, Nishio, Motohiro
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC115278/
https://ncbi.nlm.nih.gov/pubmed/12000838
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