Distinct roles for the N- and C-terminal regions in the cytotoxicity of pierisin-1, a putative ADP-ribosylating toxin from cabbage butterfly, against mammalian cells

Pierisin-1 is an 850-aa cytotoxic protein found in the cabbage butterfly, Pieris rapae, and has been suggested to consist of an N-terminal region with ADP-ribosyltransferase domain and of a C-terminal region that might have a receptor-binding domain. To elucidate the role of each region, we investig...

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Detalhes bibliográficos
Main Authors: Kanazawa, Takashi, Watanabe, Masahiko, Matsushima-Hibiya, Yuko, Kono, Takuo, Tanaka, Noriaki, Koyama, Kotaro, Sugimura, Takashi, Wakabayashi, Keiji
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30120/
https://ncbi.nlm.nih.gov/pubmed/11226221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051628898
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