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Myotubes from transgenic mdx mice expressing full-length dystrophin show normal calcium regulation.

A lack of dystrophin results in muscle degeneration in Duchenne muscular dystrophy. Dystrophin-deficient human and mouse muscle cells have higher resting levels of intracellular free calcium ([Ca2+]i) and show a related increase in single-channel open probabilities of calcium leak channels. Elevated...

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Detalhes bibliográficos
Main Authors: Denetclaw, W F, Hopf, F W, Cox, G A, Chamberlain, J S, Steinhardt, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC301138/
https://ncbi.nlm.nih.gov/pubmed/7865881
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