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Pharmacogenomics Bias - Systematic distortion of study results by genetic heterogeneity

BACKGROUND: Decision analyses of drug treatments in chronic diseases require modeling the progression of disease and treatment response beyond the time horizon of clinical or epidemiological studies. In many such models, progression and drug effect have been applied uniformly to all patients; hetero...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Siebert, Uwe, Sroczynski, Gaby, Zietemann, Vera
Format: Artigo
Sprache:Inglês
Veröffentlicht: German Medical Science GMS Publishing House 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011301/
https://ncbi.nlm.nih.gov/pubmed/21289909
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