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Pharmacogenomics Bias - Systematic distortion of study results by genetic heterogeneity

BACKGROUND: Decision analyses of drug treatments in chronic diseases require modeling the progression of disease and treatment response beyond the time horizon of clinical or epidemiological studies. In many such models, progression and drug effect have been applied uniformly to all patients; hetero...

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Hlavní autoři: Siebert, Uwe, Sroczynski, Gaby, Zietemann, Vera
Médium: Artigo
Jazyk:Inglês
Vydáno: German Medical Science GMS Publishing House 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011301/
https://ncbi.nlm.nih.gov/pubmed/21289909
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