Integrin alpha 2 cytoplasmic domain deletion effects: loss of adhesive activity parallels ligand-independent recruitment into focal adhesions.
Chinese hamster ovary (CHO) cells transfected with the integrin alpha 2 subunit formed a stable VLA-2 heterodimer that mediated cell adhesion to collagen. Within CHO cells spread on collagen, but not fibronectin, wild-type alpha 2 subunit localized into focal adhesion complexes (FACs). In contrast,...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Mol Biol Cell |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Cell Biology
1994
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7841525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.9.977 |
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