Integrin alpha 2 cytoplasmic domain deletion effects: loss of adhesive activity parallels ligand-independent recruitment into focal adhesions.

Chinese hamster ovary (CHO) cells transfected with the integrin alpha 2 subunit formed a stable VLA-2 heterodimer that mediated cell adhesion to collagen. Within CHO cells spread on collagen, but not fibronectin, wild-type alpha 2 subunit localized into focal adhesion complexes (FACs). In contrast,...

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Detalhes bibliográficos

Publicado no:	Mol Biol Cell
Principais autores:	Kawaguchi, S, Bergelson, J M, Finberg, R W, Hemler, M E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Cell Biology 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7841525/ https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.9.977
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