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Polymers for Improving the In Vivo Transduction Efficiency of AAV2 Vectors

BACKGROUND: Adeno-associated virus has attracted great attention as vehicle for body-wide gene delivery. However, for the successful treatment of a disease such as Duchenne muscular dystrophy infusion of very large amounts of vectors is required. This not only raises questions about the technical fe...

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Bibliografiska uppgifter
Huvudupphovsmän: Moulay, Gilles, Boutin, Sylvie, Masurier, Carole, Scherman, Daniel, Kichler, Antoine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011005/
https://ncbi.nlm.nih.gov/pubmed/21203395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015576
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