Transgenic Overexpression of LARGE Induces α-Dystroglycan Hyperglycosylation in Skeletal and Cardiac Muscle

BACKGROUND: LARGE is one of seven putative or demonstrated glycosyltransferase enzymes defective in a common group of muscular dystrophies with reduced glycosylation of α-dystroglycan. Overexpression of LARGE induces hyperglycosylation of α-dystroglycan in both wild type and in cells from dystroglyc...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Brockington, Martin, Torelli, Silvia, Sharp, Paul S., Liu, Ke, Cirak, Sebahattin, Brown, Susan C., Wells, Dominic J., Muntoni, Francesco
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2010
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010994/
https://ncbi.nlm.nih.gov/pubmed/21203384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014434
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