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Cell cycle-regulated degradation of Xenopus cyclin B2 requires binding to p34cdc2.

The protein kinase activity of the cell cycle regulator p34cdc2 is inactivated when the mitotic cyclin to which it is bound is degraded. The amino (N)-terminus of mitotic cyclins includes a conserved "destruction box" sequence that is essential for degradation. Although the N-terminus of sea urchin...

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Publicat a:Mol Biol Cell
Autors principals: van der Velden, H M, Lohka, M J
Format: Artigo
Idioma:Inglês
Publicat: American Society for Cell Biology 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC301090/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7812041/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.5.7.713
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