Cholesterol lipids of Borrelia burgdorferi form lipid rafts and are required for the bactericidal mechanism of a complement-independent antibody

Borrelia burgdorferi (the agent of Lyme disease) is unusual in that it contains free cholesterol and cholesterol glycolipids. It is also susceptible to complement-independent bactericidal antibodies, such as CB2, a monoclonal IgG1 against outer surface protein B (OspB). The bactericidal action of CB...

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Autors principals: LaRocca, Timothy J, Crowley, Jameson T, Cusack, Brian J, Pathak, Priyadarshini, Benach, Jordi, London, Erwin, Garcia-Monco, Juan C, Benach, Jorge L
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010898/
https://ncbi.nlm.nih.gov/pubmed/20951967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.09.001
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