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Cdc25A-Driven Proliferation Regulates CD62L Levels and Lymphocyte Movement in Response to Interleukin-7

OBJECTIVE: IL-7 is a multifunctional cytokine and a promising immunotherapeutic agent. However, since a transient T-cell depletion is an immediate outcome of IL-7 administration at supraphysiological doses, we investigated the mechanism by which the IL-7 proliferative signal transduced through Cdc25...

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Detalhes bibliográficos
Main Authors: Kittipatarin, Christina, Li, Wenqing, Durum, Scott K., Khaled, Annette R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010876/
https://ncbi.nlm.nih.gov/pubmed/20831893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2010.08.010
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