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The Interaction of LCK and the CD4 Co-receptor Alters the Dose Response of T-cells to Interleukin-7
CD8 and CD4 T-cells grow optimally under different concentrations of the cytokine, interleukin-7 (IL-7). While CD8 T-cells expand at high doses of IL-7, CD4 T-cells favor low doses. To examine the reason for the preference of CD4 T-cells for lower doses of the cytokine, we used IL-7-dependent T-cell...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892797/ https://ncbi.nlm.nih.gov/pubmed/20433867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2010.04.007 |
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