Antibody-Unfolding and Metastable-State Binding in Force Spectroscopy and Recognition Imaging

Force spectroscopy and recognition imaging are important techniques for characterizing and mapping molecular interactions. In both cases, an antibody is pulled away from its target in times that are much less than the normal residence time of the antibody on its target. The distribution of pulling l...

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Main Authors: Kaur, Parminder, Qiang-Fu, Fuhrmann, Alexander, Ros, Robert, Kutner, Linda Obenauer, Schneeweis, Lumelle A., Navoa, Ryman, Steger, Kirby, Xie, Lei, Yonan, Christopher, Abraham, Ralph, Grace, Michael J., Lindsay, Stuart
格式: Artigo
語言:Inglês
出版: The Biophysical Society 2011
主題:
Spectroscopy, Imaging, and Other Techniques
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010837/
https://ncbi.nlm.nih.gov/pubmed/21190677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.050
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