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Antibody-Unfolding and Metastable-State Binding in Force Spectroscopy and Recognition Imaging

Force spectroscopy and recognition imaging are important techniques for characterizing and mapping molecular interactions. In both cases, an antibody is pulled away from its target in times that are much less than the normal residence time of the antibody on its target. The distribution of pulling l...

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Autori principali: Kaur, Parminder, Qiang-Fu, Fuhrmann, Alexander, Ros, Robert, Kutner, Linda Obenauer, Schneeweis, Lumelle A., Navoa, Ryman, Steger, Kirby, Xie, Lei, Yonan, Christopher, Abraham, Ralph, Grace, Michael J., Lindsay, Stuart
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010837/
https://ncbi.nlm.nih.gov/pubmed/21190677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.11.050
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