Dendritic Cells in Lupus are not Required for Activation of T and B Cells but Promote their Expansion Resulting in Tissue Damage

Dendritic cells (DCs) initiate and control the adaptive immune response against infections. However, their contributions to the anti-self adaptive immune response in autoimmune disorders like systemic lupus erythematosus are uncertain. By constitutively deleting DCs in MRL.Fas(lpr) mice we show that...

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Hlavní autoři: Teichmann, Lino L., Ols, Michelle L., Kashgarian, Michael, Reizis, Boris, Kaplan, Daniel H., Shlomchik, Mark J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010763/
https://ncbi.nlm.nih.gov/pubmed/21167752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.11.025
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