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Selective knockdown of NMDA receptors in primary afferent neurons decreases pain during phase 2 of the formalin test

The role of NMDA receptors (NMDARs) expressed by primary afferent neurons in nociception remains controversial. The aim of this study was to develop mice with a tissue selective knockdown of NMDARs in these neurons and to evaluate their behavioral responses to different types of painful stimuli. Mic...

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Detalhes bibliográficos
Main Authors: McRoberts, James A., Ennes, Helena S., Marvizón, Juan Carlos G., Fanselow, Michael S., Mayer, Emeran A., Vissel, Bryce
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010451/
https://ncbi.nlm.nih.gov/pubmed/20974228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.10.045
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