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Structure-based design of NS2 mutants for attenuated influenza A virus vaccines
We previously characterized the matrix 1 (M1)-binding domain of the influenza A virus NS2/nuclear export protein (NEP), reporting a critical role for the tryptophan (W78) residue that is surrounded by a cluster of glutamate residues in the C-terminal region that interacts with the M1 protein (Akarsu...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3010430/ https://ncbi.nlm.nih.gov/pubmed/20970464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2010.10.014 |
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