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Synthesis of Macrocyclic Tetrazoles for Rapid Photoinduced Bioorthogonal 1,3-Dipolar Cycloaddition Reactions

A series of conformationally constrained, macrocyclic tetrazoles were expediently prepared by double alkylation of a bis(o-phenolyl)tetrazole precursor. Several of them showed excellent reactivity toward norbornene in a photoinduced tetrazole-alkene cycloaddition reaction in organic solvent as well...

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Detalhes bibliográficos
Main Authors: Yu, Zhipeng, Lim, Reyna K. V., Lin, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010379/
https://ncbi.nlm.nih.gov/pubmed/21031376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201002360
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