Regulation of specific target genes and biological responses by estrogen receptor subtype agonists

Estrogenic effects are mediated through two estrogen receptor (ER) subtypes, ERα and ERβ. Estrogens are the most commonly prescribed drugs to treat menopausal conditions, but by non-selectively triggering both ERα and ERβ pathways in different tissues they can cause serious adverse effects. The diff...

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Bibliografiske detaljer
Main Authors: Leitman, Dale C., Paruthiyil, Sreenivasan, Vivar, Omar I., Saunier, Elise F., Herber, Candice B., Cohen, Isaac, Tagliaferri, Mary, Speed, Terence P.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010356/
https://ncbi.nlm.nih.gov/pubmed/20951642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2010.09.009
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