Cell type- and estrogen receptor-subtype specific regulation of selective estrogen receptor modulator regulatory elements

Selective estrogen receptor modulators (SERMs), such as tamoxifen and raloxifene can act as estrogen receptor (ER) antagonists or agonists depending on the cell type. The antagonistic action of tamoxifen has been invaluable for treating breast cancer, whereas the agonist activity of SERMs also has i...

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Главные авторы: Ball, Lonnele J., Levy, Nitzan, Zhao, Xiaoyue, Griffin, Chandi, Tagliaferri, Mary, Cohen, Isaac, Ricke, William A., Speed, Terence P., Firestone, Gary L., Leitman, Dale C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420066/
https://ncbi.nlm.nih.gov/pubmed/19059307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2008.10.050
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