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Lactate per se improves the excitability of depolarized rat skeletal muscle by reducing the Cl(−) conductance

Studies on rats have shown that lactic acid can improve excitability and function of depolarized muscles. The effect has been related to the ensuing reduction in intracellular pH causing inhibition of muscle fibre Cl(−) channels. However, since several carboxylic acids with structural similarities t...

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Detalhes bibliográficos
Main Authors: de Paoli, Frank Vincenzo, Ørtenblad, Niels, Pedersen, Thomas Holm, Jørgensen, Rasmus, Nielsen, Ole Bækgaard
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010146/
https://ncbi.nlm.nih.gov/pubmed/20876199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.196568
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