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An atlas of gene regulatory networks reveals multiple three-gene mechanisms for interpreting morphogen gradients

The interpretation of morphogen gradients is a pivotal concept in developmental biology, and several mechanisms have been proposed to explain how gene regulatory networks (GRNs) achieve concentration-dependent responses. However, the number of different mechanisms that may exist for cells to interpr...

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Autori principali: Cotterell, James, Sharpe, James
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010108/
https://ncbi.nlm.nih.gov/pubmed/21045819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.74
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