The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1

The ankyrin transient receptor potential channel TRPA1 is a non-selective cationic channel that is expressed by sensory neurons, where it can be activated by pungent chemicals, such as AITC (allyl isothiocyanate), cinnamon or allicin, by deep cooling (<18 °C) or highly depolarizing voltages (>...

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Detalhes bibliográficos
Main Authors: Samad, Abdul, Sura, Lucie, Benedikt, Jan, Ettrich, Rudiger, Minofar, Babak, Teisinger, Jan, Vlachova, Viktorie
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010083/
https://ncbi.nlm.nih.gov/pubmed/20946100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101256
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