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Conserved Residues within the Putative S4–S5 Region Serve Distinct Functions among Thermosensitive Vanilloid Transient Receptor Potential (TRPV) Channels

The vanilloid transient receptor potential channel TRPV1 is a tetrameric six-transmembrane segment (S1–S6) channel that can be synergistically activated by various proalgesic agents such as capsaicin, protons, heat, or highly depolarizing voltages, and also by 2-aminoethoxydiphenyl borate (2-APB), a...

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Autori principali: Boukalova, Stepana, Marsakova, Lenka, Teisinger, Jan, Vlachova, Viktorie
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009871/
https://ncbi.nlm.nih.gov/pubmed/21044960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.145466
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