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Neuropeptide Y Modulation of Interleukin-1β (IL-1β)-induced Nitric Oxide Production in Microglia

Given the modulatory role of neuropeptide Y (NPY) in the immune system, we investigated the effect of NPY on the production of NO and IL-1β in microglia. Upon LPS stimulation, NPY treatment inhibited NO production as well as the expression of inducible nitric-oxide synthase (iNOS). Pharmacological s...

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Bibliografiske detaljer
Main Authors: Ferreira, Raquel, Xapelli, Sara, Santos, Tiago, Silva, Ana Paula, Cristóvão, Armando, Cortes, Luísa, Malva, João O.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009919/
https://ncbi.nlm.nih.gov/pubmed/20959451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164020
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