An Interleukin-1β (IL-1β) Single-Nucleotide Polymorphism at Position 3954 and Red Complex Periodontopathogens Independently and Additively Modulate the Levels of IL-1β in Diseased Periodontal Tissues

Inflammatory cytokines such as interleukin-1β (IL-1β) are involved in the pathogenesis of periodontal diseases. A high individual variation in the levels of IL-1β mRNA has been verified, which is possibly determined by genetic polymorphisms and/or by the presence of periodontopathogens such as Porph...

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Bibliografski detalji
Glavni autori: Ferreira, Samuel B., Trombone, Ana Paula F., Repeke, Carlos E., Cardoso, Cristina R., Martins, Walter, Santos, Carlos F., Trevilatto, Paula Cristina, Ávila-Campos, Mario J., Campanelli, Ana Paula, Silva, João S., Garlet, Gustavo P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2008
Teme:
Host Response and Inflammation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2493201/
https://ncbi.nlm.nih.gov/pubmed/18541658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00546-08
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