Cross talk among tyrosine kinase receptors in PC12 cells: desensitization of mitogenic epidermal growth factor receptors by the neurotrophic factors, nerve growth factor and basic fibroblast growth factor.

We have studied the effects of nerve growth factor (NGF) and basic fibroblast growth factor (bFGF) on epidermal growth factor (EGF) binding to PC12 cells. We show that NGF and bFGF rapidly induce a reduction in 125I-EGF binding to PC12 cells in a dose-dependent manner. This decrease amounts to 50% f...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Mol Biol Cell
Auteurs principaux: Mothe, I, Ballotti, R, Tartare, S, Kowalski-Chauvel, A, Van Obberghen, E
Format: Artigo
Langue:Inglês
Publié: American Society for Cell Biology 1993
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300983/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8400459/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.7.737
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires