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MyoD induced cell cycle arrest is associated with increased nuclear affinity of the Rb protein.

In studying the mechanism through which the myogenic determination protein MyoD prevents entry into the S phase of the cell cycle, we have found a relationship between MyoD and the retinoblastoma (Rb) tumor suppressor protein. By direct needle microinjection of purified recombinant MyoD protein into...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: Thorburn, A M, Walton, P A, Feramisco, J R
Format: Artigo
Language:Inglês
Published: American Society for Cell Biology 1993
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8400456/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.4.7.705
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