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MyoD induced cell cycle arrest is associated with increased nuclear affinity of the Rb protein.

In studying the mechanism through which the myogenic determination protein MyoD prevents entry into the S phase of the cell cycle, we have found a relationship between MyoD and the retinoblastoma (Rb) tumor suppressor protein. By direct needle microinjection of purified recombinant MyoD protein into...

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Bibliographic Details
Main Authors: Thorburn, A M, Walton, P A, Feramisco, J R
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC300980/
https://ncbi.nlm.nih.gov/pubmed/8400456
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