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Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a

FOXO transcription factors are key tumor suppressors in mammalian cells. Until now, suppression of FOXOs in cancer cells was thought to be mainly due to activation of multiple onco-kinases by a phosphorylation-ubiquitylation-mediated cascade. Therefore, it was speculated that inhibition of FOXO prot...

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Bibliografski detalji
Glavni autori: Lin, Huanxin, Dai, Ting, Xiong, Huaping, Zhao, Xiaohui, Chen, Xiuting, Yu, Chunping, Li, Jun, Wang, Xi, Song, Libing
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009749/
https://ncbi.nlm.nih.gov/pubmed/21203424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015797
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