Loss of Caveolin-1 Accelerates Neurodegeneration and Aging

BACKGROUND: The aged brain exhibits a loss in gray matter and a decrease in spines and synaptic densities that may represent a sequela for neurodegenerative diseases such as Alzheimer's. Membrane/lipid rafts (MLR), discrete regions of the plasmalemma enriched in cholesterol, glycosphingolipids,...

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Detalhes bibliográficos
Main Authors: Head, Brian P., Peart, Jason N., Panneerselvam, Mathivadhani, Yokoyama, Takaakira, Pearn, Matthew L., Niesman, Ingrid R., Bonds, Jacqueline A., Schilling, Jan M., Miyanohara, Atsushi, Headrick, John, Ali, Sameh S., Roth, David M., Patel, Piyush M., Patel, Hemal H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009734/
https://ncbi.nlm.nih.gov/pubmed/21203469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015697
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