Loss of Caveolin-1 Accelerates Neurodegeneration and Aging

BACKGROUND: The aged brain exhibits a loss in gray matter and a decrease in spines and synaptic densities that may represent a sequela for neurodegenerative diseases such as Alzheimer's. Membrane/lipid rafts (MLR), discrete regions of the plasmalemma enriched in cholesterol, glycosphingolipids,...

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Bibliografski detalji
Glavni autori: Head, Brian P., Peart, Jason N., Panneerselvam, Mathivadhani, Yokoyama, Takaakira, Pearn, Matthew L., Niesman, Ingrid R., Bonds, Jacqueline A., Schilling, Jan M., Miyanohara, Atsushi, Headrick, John, Ali, Sameh S., Roth, David M., Patel, Piyush M., Patel, Hemal H.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009734/
https://ncbi.nlm.nih.gov/pubmed/21203469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015697
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