Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1

Epstein-Barr virus (EBV) is associated with human malignancies, especially those affecting the B cell compartment such as Burkitt lymphoma. The virally encoded homolog of the mammalian pro-survival protein Bcl-2, BHRF1 contributes to viral infectivity and lymphomagenesis. In addition to the pro-apop...

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Detalhes bibliográficos
Main Authors: Kvansakul, Marc, Wei, Andrew H., Fletcher, Jamie I., Willis, Simon N., Chen, Lin, Roberts, Andrew W., Huang, David C. S., Colman, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009601/
https://ncbi.nlm.nih.gov/pubmed/21203485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001236
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