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An integrative modular approach to systematically predict gene-phenotype associations

BACKGROUND: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these complex phenotypes, we developed a network-based approach to identify coexpression modules specifically activated in particu...

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Detalhes bibliográficos
Main Authors: Mehan, Michael R, Nunez-Iglesias, Juan, Dai, Chao, Waterman, Michael S, Zhou, Xianghong Jasmine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009536/
https://ncbi.nlm.nih.gov/pubmed/20122238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S1-S62
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