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Epac2-Dependent Rap1 Activation and the Control of Islet Insulin Secretion by Glucagon-Like Peptide-1

Glucagon-like peptide-1 (GLP-1) binds its Class II G protein-coupled receptor to stimulate cyclic adenosine monophosphate (cAMP) production and to potentiate the glucose metabolism-dependent secretion of insulin from pancreatic β cells located within the islets of Langerhans. Prior clinical studies...

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Autors principals: Leech, Colin A., Chepurny, Oleg G., Holz, George G.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009389/
https://ncbi.nlm.nih.gov/pubmed/21094904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-381517-0.00010-2
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