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The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling

BACKGROUND: NFκB signaling is of paramount importance in the regulation of apoptosis, proliferation, and inflammatory responses during human development and homeostasis, as well as in many human cancers. Receptor Tyrosine Kinases (RTKs), including the Fibroblast Growth Factor Receptors (FGFRs) are a...

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Autores principales: Drafahl, Kristine A., McAndrew, Christopher W., Meyer, April N., Haas, Martin, Donoghue, Daniel J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008709/
https://ncbi.nlm.nih.gov/pubmed/21203561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014412
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