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The Receptor Tyrosine Kinase FGFR4 Negatively Regulates NF-kappaB Signaling

BACKGROUND: NFκB signaling is of paramount importance in the regulation of apoptosis, proliferation, and inflammatory responses during human development and homeostasis, as well as in many human cancers. Receptor Tyrosine Kinases (RTKs), including the Fibroblast Growth Factor Receptors (FGFRs) are a...

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Detalhes bibliográficos
Main Authors: Drafahl, Kristine A., McAndrew, Christopher W., Meyer, April N., Haas, Martin, Donoghue, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008709/
https://ncbi.nlm.nih.gov/pubmed/21203561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014412
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