The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish

The Frizzled receptor and Dishevelled effector regulate mitotic spindle orientation in both vertebrates and invertebrates, but how Dishevelled orients the mitotic spindle is unknown. Using the Drosophila S2 cell "induced polarity" system, we find that Dishevelled cortical polarity is suffi...

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Autores principales: Ségalen, Marion, Johnston, Christopher A., Martin, Charlotte A., Dumortier, Julien G., Prehoda, Kenneth E., David, Nicolas B., Doe, Chris Q., Bellaïche, Yohanns
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008569/
https://ncbi.nlm.nih.gov/pubmed/21074723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.10.004
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