The Fz-Dsh planar cell polarity pathway induces oriented cell division via Mud/NuMA in Drosophila and zebrafish

The Frizzled receptor and Dishevelled effector regulate mitotic spindle orientation in both vertebrates and invertebrates, but how Dishevelled orients the mitotic spindle is unknown. Using the Drosophila S2 cell "induced polarity" system, we find that Dishevelled cortical polarity is suffi...

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Detalhes bibliográficos
Main Authors: Ségalen, Marion, Johnston, Christopher A., Martin, Charlotte A., Dumortier, Julien G., Prehoda, Kenneth E., David, Nicolas B., Doe, Chris Q., Bellaïche, Yohanns
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008569/
https://ncbi.nlm.nih.gov/pubmed/21074723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.10.004
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