Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain

Recent studies indicate that tissue factor (TF) acts in embryogenesis, metastasis, and angiogenesis. Three independent groups showed that targeted disruption of the murine TF (mTF) gene results in 90% lethality of mTF null embryos at embryonic days 9.5–10.5. We have demonstrated that expression of w...

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Pubblicato in:	J Clin Invest
Autori principali:	Parry, Graham C.N., Mackman, Nigel
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 2000
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300856/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841513/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9458
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