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Mouse embryogenesis requires the tissue factor extracellular domain but not the cytoplasmic domain

Recent studies indicate that tissue factor (TF) acts in embryogenesis, metastasis, and angiogenesis. Three independent groups showed that targeted disruption of the murine TF (mTF) gene results in 90% lethality of mTF null embryos at embryonic days 9.5–10.5. We have demonstrated that expression of w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Parry, Graham C.N., Mackman, Nigel
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC300856/
https://ncbi.nlm.nih.gov/pubmed/10841513
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