Sensitive Assay for Quantification of Hepatitis B Virus Mutants by Use of a Minor Groove Binder Probe and Peptide Nucleic Acids

Lamivudine is the first nucleoside analogue that was shown to have a potent effect on hepatitis B virus (HBV). However, the emergence of mutants resistant or cross-resistant to nucleoside/nucleotide analogues remains a serious problem. Several assays for the detection and quantification of antiviral...

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Autors principals: Hige, Shuhei, Yamamoto, Yoichi, Yoshida, Shigeru, Kobayashi, Tomoe, Horimoto, Hiromasa, Yamamoto, Keiko, Sho, Takuya, Natsuizaka, Mitsuteru, Nakanishi, Mitsuru, Chuma, Makoto, Asaka, Masahiro
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Virology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008448/
https://ncbi.nlm.nih.gov/pubmed/20926703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00731-10
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